The Oncology Institute of Hope and Innovation is a leader in clinical trials. Our goal: to advance the treatment of cancer. Our team currently conducts clinical trials for virtually every type of cancer, and we constantly enroll patients in new trials to ensure they have access to the latest therapeutics appropriate for their clinical condition.
Interested in participating in a clinical trial? Following is some helpful information to help you decide.
A cancer treatment clinical trial is a study conducted with patients in order to evaluate the safety and effectiveness of a new therapy, diagnostic test, or prevention method. A clinical trial also helps determine new ways to use current therapies and drugs.
Clinical trials are conducted in four phases. The FDA requires clinical trials before any kind of medicine can be approved for the general population.
Clinical trial conductors sign up patients to participate. Without patients, there would be no clinical trials!
All clinical trials have guidelines about who can participate in order to ensure reliable results. The factors that allow someone to participate in a clinical trial are called “inclusion criteria” and those that disallow someone from participating are called “exclusion criteria.”
Before joining a clinical trial, a participant must qualify for the study.
Sometimes, completely healthy people are needed, while at other times, people with specific illnesses and conditions are required.
Absolutely! Your safety is our priority during your participation in a clinical trial!
Your participation is completely voluntary. You may withdraw from the trial at any time if you start to feel uncomfortable.
If you qualify for one of our studies, we will discuss the details of the trial. This is called the “informed consent” process.
This helps you and your family understand the key elements of the trial including:
This is also the time for you to ask any questions you may have.
You will be closely monitored throughout the trial by our highly trained and dedicated physicians and staff to ensure your safety. We take care of our patients as if they were our family.
1. You will be a part of an effort for the greater good. A steady supply of patients is needed to keep clinical trials going. The more patients who participate, the greater the chance we achieve a breakthrough in medicine.
2. You will have access to medication or treatments that aren’t available to the general public. You may be among the first to benefit from the latest cutting-edge research as it moves out of the laboratory and into doctors’ hands.
3. You will play an active role in your healthcare—and in the process, learn much more about your particular healthcare condition.
4. You will receive the highest level of personal medical attention, along with trial supplies, trial lab services, and trial medicine at no cost.
Phase I trials help researchers determine the most appropriate dosage and to identify any side effects that may be associated with the new treatment. This phase also helps determine the best way to deliver the new treatment—for example, if a drug should be given by injection or by mouth. Phase I trials typically involve fewer than 100 participants.
Phase II trials test the treatment in patients who have the targeted medical condition in order to begin determining its effectiveness. Researchers continue to track the drug’s safety and side effects. Phase II trials involve more patients but are still very limited in size.
Phase III trials compare the new treatment to one or more standard therapies currently in use among patients. The new treatment is sometimes combined with established therapies to determine if the combination is more effective than standard therapy alone. Safety and side effects continue to be tracked as the trial expands to include hundreds or even thousands of patients.
Phase IV trials can begin once the treatment is approved for general use to continue to monitor its safety and effectiveness and to give researchers and physicians additional information about how best to employ the new treatment.
The sponsor can be the pharmaceutical company, research institution, or health organization that funds a clinical trial. This funding source can be a commercial enterprise, a governmental agency, or a philanthropic organization.
The Oncology Institute of Hope and Innovation currently conducts numerous clinical trials on cutting-edge cancer treatments.